Strawberry, bitter melon juices + anti-inflammatory

Since we're doing anti-inflammatory for the last weeks of the semester i thought id look up easily accessible foods that has anti-inflammatory effects. I found an article by J-Y. Lin and C-Y Tang who conducted an experiments on strawberries, loquat, mulberry and bitter melon juices to examine their anti-inflammatory effects on LPS-stimulated peritoneal macrophages cultures taken from mice. Lin and Tang chose these fruits/vegetable because of their properties that exhibit anti-inflammatory responses from previous experiments. It has been found that fruits such as strawberries contain compounds that inhibits COX activity and have demonstrated that it has an anticancer activity as well while mulberry fruit extracts inhibit atherosclerosis on rats in cholesterol-rich diets and bitter melon are used in traditional medicine by Asian countries as treatment for diabetes. What they found was that

The fruit juice extracts were taken from strawberry, loquat, mulberry and bitter melon bought from a supermarket in Taiwan. Peritoneal macrophages were taken from mice and divided into 3 different LPS-induced inflammation models. Model A was an inflammation-prophylactic cell culture (peritoneal macrophages were exposed to 0, 10 and 500 microgram/ml concentration of fruit juices before LPS stimulation), model B was designed where peritoneal macrophage cell cultures were first stimulated with LPS then administered 0, 10 and 500 microgram/ml concentration of fruit juices and model C was designed to examine the effects of fruit juice administration to cell upon cytokine production clearance with simultaneous acute LPS stimulation. What they found was that loquat, bitter melon and mulberry administration significantly decreased levels of pro-inflammatory cytokines while strawberry (along with the other fruits/veg.) increased IL-10 production in dose-dependent experiment model A. Administration of bitter melon and loquat also significantly increased IL-10 production in model C, suggesting that strawberry, loquat, mulberry and bitter melon all have prophylactic anti-inflammatory properties by decreasing pro-inflammatory cytokines (IL-1beta, IL-6 and TNF-alpha) and increasing anti-inflammatory cytokine (IL-10) production in LPS-induced inflammation in mice peritoneal macrophages.

So, eat your fruits and vegetables :)!

http://web.ebscohost.com.ezproxy1.library.arizona.edu/ehost/detail?vid=2&hid=114&sid=194fc15b-49fb-421c-a4b9-411eb893a794%40sessionmgr107