tag:blogger.com,1999:blog-42721667635011586552011-07-08T00:20:30.647-06:00JJ Cohenhttp://www.blogger.com/profile/09644112725589362934noreply@blogger.comBlogger1971100tag:blogger.com,1999:blog-4272166763501158655.post-70106438078490245852008-05-14T18:00:00.001-06:002008-05-14T18:02:49.073-06:00

Several blogs have been devoted to the awareness of anti-inflammatory foods and what they are. This blog is different. Today I’m going to inform all of you which foods are actually pro-inflammatory. You might think you know which foods cause inflammation, but you have no idea(haha). According to Bonnie C. Minsky writer of “Inflammation = Degenerative Disease” the pro-inflammatory foods to

BrookeJhttp://www.blogger.com/profile/00218243495690964892noreply@blogger.com13tag:blogger.com,1999:blog-4272166763501158655.post-42092060894775093202008-05-12T11:41:00.001-06:002008-05-12T11:42:28.438-06:00

To eat or not to eat chocolate, that is the question. Studies are popping up everywhere regarding the health effects of flavanol-rich cocoa on the body’s cardiovascular system. Such a study was performed by researchers from Harvard Medical School and the Brigham and Women’s Hospital in Boston. Participants included 15 healthy adults under the age of 50 and 19 healthy adults over the age of 50.

BrookeJhttp://www.blogger.com/profile/00218243495690964892noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-9170474095013670532008-05-11T23:00:00.001-06:002008-05-11T23:01:43.057-06:00

Lupus has been my latest inquiry. A small, probably, unnoticeable segment connected to the very last page of the “Modulation of cell recruitment by anti-inflammatory agents in antigen-induced arthritis,” article had a memorable picture regarding a lupus case. The real eye catcher wasn’t the enormous butterfly tattoo on the 33 year old woman’s back, but the “ginormous” blotchy red lesion above

BrookeJhttp://www.blogger.com/profile/00218243495690964892noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-24582517517541603592008-05-10T22:12:00.001-06:002008-05-10T22:14:17.988-06:00

Going back to the neuro articles the thing that really stands out to me is how fibrin is concsidered the new target for Alzheimer’s disease. Fibrin correlates to beta-amyloid protein build-up in Alzheimer’s. As the beta-amyloid protein accumulates so does fibrin. According to Justin Paul, a graduate student, and Sidney Strickland, head of the Laboratory of Neurobiology and Genetics, fibrin could

BrookeJhttp://www.blogger.com/profile/00218243495690964892noreply@blogger.com2tag:blogger.com,1999:blog-4272166763501158655.post-75439947784461122372008-05-10T00:31:00.002-06:002008-05-10T00:36:55.117-06:00

I am amazed at all the anti-inflammatory foods posted by my fellow classmates in this forum. I did some websuring just to see what other unusual things are claimed to have anti-inflammatory properties. Suprisingly and to my relief, I found that grass fed beef (as opposed to grain-fed) and other animal foods may offer some protection from inflammation. Meat from grass-fed animals supposedly has

Etorda B.http://www.blogger.com/profile/15565201901200163473noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-10279948457879530292008-05-07T15:31:00.002-06:002008-05-07T15:40:59.228-06:00

Doctors and researchers at Mayo Clinic in Rochester, Minn have proven studies that patients with rheumatoid arthritis are at a much greater risk for unrecognized heart disease and cardiac sudden death.* The risk of heart attack is already there at the time a rheumatoid arthritis diagnosis is first made. * Heart disease can remain silent in those with rheumatoid arthritis. Regular cardiac

KristenL495http://www.blogger.com/profile/08000688165995634035noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-45133931016039050702008-05-07T13:19:00.010-06:002008-05-07T13:45:45.391-06:00

After reading 'Active spice-derived components can inhibit inflammatory responses of adipose tissue in obesity by suppressing inflammatory actions of macrophages and release of MCP-1 from adipocytes' article, i found another article that talks about a substance inhibiting MCP-1 activity. Dehydroabietic acid (DAA) is an abietic acid derivative contained in Terpenoids of many herbal and dietary

arlenej495http://www.blogger.com/profile/16614963142751531502noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-68601696239777905042008-05-07T12:10:00.000-06:002008-05-07T12:11:08.826-06:00

After reading the article “Turmeric extracts containing curcuminoids prevent experimental Rheumatoid arthritis” by Janet Funk I wanted to find out a little more about Ayurvedic medicine. In particular I wanted find out what other herbs they believe to have helpful or healing powers. I found a list on Wikipedia called the “list of herbs and minerals in Aryuveda, and most of them have the

Ashleym495http://www.blogger.com/profile/14392001097313294780noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-76192421411231997542008-05-07T11:40:00.000-06:002008-05-07T11:41:28.059-06:00

I have a strong interest in integrative medicine and I think complimenting modern medicine with Ayurvedic practices is a good idea. But upon doing some research I think there is an area where people should limit their intake. The Center for Disease Control found that, “Some Ayurvedic medicines contain metals and minerals that can lead to toxicity of the liver. “During 2000-2003, a total of 12

lhtsosiehttp://www.blogger.com/profile/14584306614655142149noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-80846640463707144082008-05-07T00:38:00.002-06:002008-05-07T01:14:46.411-06:00

Since most of the articles this week focused on spices, I did some more research on anti-inflammatory spices. I found that the top 12 anti-inflammatory spices are Ginger, Turmeric, Black Pepper, Cinnamon, Rosemary, Basil, Cardamon, Chives, Cilantro ,Cloves, Garlic, and Parsley. There seemed to be the most information on Turmeric though. Turmeric is a spice that belongs to the ginger family and it

MargaretO495http://www.blogger.com/profile/09079283530627304529noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-64425360394036845202008-05-06T09:24:00.001-06:002008-05-06T09:26:36.260-06:00

Turmeric is a perennial native to Asia that has been used in traditional medicine for the treatment of inflammatory disorders. This experiment studied its efficacy of curcuminoid-containing turmeric extracts in prevention/treatment of Rheumatoid arthritis. An essential oil-depleted turmeric fraction(41% of the three major curcuminoids) was effective in preventing joint inflammation in both the

JackieE499http://www.blogger.com/profile/00569628992122703068noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-39377705852788923922008-05-05T18:49:00.005-06:002008-05-05T19:25:00.002-06:00

Since we're doing anti-inflammatory for the last weeks of the semester i thought id look up easily accessible foods that has anti-inflammatory effects. I found an article by J-Y. Lin and C-Y Tang who conducted an experiments on strawberries, loquat, mulberry and bitter melon juices to examine their anti-inflammatory effects on LPS-stimulated peritoneal macrophages cultures taken from mice. Lin

arlenej495http://www.blogger.com/profile/16614963142751531502noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-35422852082116297702008-05-05T13:52:00.002-06:002008-05-05T14:05:23.872-06:00

I remember reading an article earlier in the semester that used Bee Venom as an alternative treatment for patients suffering with MS. Now it's potentially helpful in arthritis?The paper "Bee Venom Pretreatment Has Both an Antinociceptive and Anti-inflammatory Effect of Carrageenan-Induced Inflammation", Lee et.al. provided some very interesting informmation that under normal conditions, bee

KimiH492http://www.blogger.com/profile/18216005063376928535noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-49571280791453981452008-05-05T02:32:00.002-06:002008-05-05T02:49:15.765-06:00

While reading the article outlining the antinociceptive and anti-inflammatory effects of bee venom, I realized I had no idea what carrageenan or Fos were. These were both key components of the paper and so I decided to define both terms as best I could in order to clarify for any other uniformed people like myself. :)Carrageenans are a group of substances composed of linear sulphated

SarahD495http://www.blogger.com/profile/09996651755315338786noreply@blogger.com2tag:blogger.com,1999:blog-4272166763501158655.post-53410707219343835972008-05-05T02:18:00.003-06:002008-05-05T02:31:41.503-06:00

I find it very interesting that so many people are willing to be treated with bee venom to cure their ailments. Many people even prefer it to western medicine, or at least many people, especially in Asia find it an affordable alternative to mainstream health care. I'd like to encourage everyone to read the information on the alternative medicine of bee sting venom and its popular use at the

SarahD495http://www.blogger.com/profile/09996651755315338786noreply@blogger.com2tag:blogger.com,1999:blog-4272166763501158655.post-55982179039140656712008-05-04T20:52:00.002-06:002008-05-04T20:59:14.279-06:00

Over the weekend I was talking to a friend that told me about an oil detox treatment. I was curious about it and decided to investigate more on this treatment. The name of the treatment is Oil Pulling Therapy. Oil Pulling Therapy consists of thoroughly sloshing certain types of common oils (sunflower or sesame) in the mouth for approximately 20 minutes. Swishing is believed to activate the

MariaO495noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-88629355685327681762008-05-04T14:44:00.005-06:002008-05-04T14:53:51.618-06:00

To add to the previous post of natural alternatives as anti-inflammatory, here is an article discussing a natural healthy approach to increasing the efficacy of antibiotics. I happened to come across this article from discoveryhealth.com and thought it might be of some interest since there have been many encouraging words from multiple sources about the benefits of green tea in ones daily

LianH495http://www.blogger.com/profile/05916419830794686951noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-66469694223936989502008-05-03T14:34:00.002-06:002008-05-03T14:38:05.407-06:00

I was interested in seeing what other alternatives there are out there as far as ant inflammatories go so I googled it. I came upon an interesting article. The article had the following suggestions:1. Omega-3 Fatty Acids From Fish Oils: The omega-3 fats EPA and DHA found in fish oil have been found by many animal and clinical studies to possess anti-inflammatory properties that promote joint

ChristinaS495http://www.blogger.com/profile/02690755343984973920noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-3715608227118121352008-04-30T21:30:00.000-06:002008-04-30T22:34:05.358-06:00

New studies show that maybe Botulinium type A (Botox) may help pain and function of arthritic patients. There was a study conducted in 2006 published in Neurotoxicity Research that tested Botox injection efficacy among 11 patients with different forms of arthritis. The subject group was given one or more Botox injections within the afflicted joint, and then followed for a year post-treatment. 

KristenL495http://www.blogger.com/profile/08000688165995634035noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-79442265787835121222008-04-30T15:40:00.000-06:002008-04-30T15:41:25.703-06:00

After reading the Great Debate, I wanted to find out more about the south beach diet.I read that it is a three phase plan and that its claim to fame is that you will loose the weight you need to loose and that it will improve your cardiovascular system. I really liked that the system was a life long program however; I thought that some things needed to be changed.It states that phase 1 is two

Ashleym495http://www.blogger.com/profile/14392001097313294780noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-31082748535853480312008-04-29T18:43:00.004-06:002008-04-29T19:18:07.800-06:00

In this weeks lay article, "The Great Diet Debate" two Dr's debated over The South Beach Heart Program. Dr. Agatston, the author of the book, claims this program will detect, prevent, and even reverse heart disease although a study showed this diet did not lower LDL cholesterol levels. Dr. Agatston also prescribes his patients drugs to lower their LDL cholesterol instead of advising them to eat

MargaretO495http://www.blogger.com/profile/09079283530627304529noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-6258611300704613542008-04-28T14:25:00.003-06:002008-04-28T14:39:33.629-06:00

A major cause of inflammation in our bodies is the food we eat. Inflammation can be aggravated by diets high in refined or hydrogenated vegetable oils such as those found in margarines, potato chips and baked goods and by diets high in sugars. Food can also be part of the solution to inflammation; anti-inflammatory foods, if eaten regularly, can reduce inflammation in the body. Vegetables: Bell

AshleyF495http://www.blogger.com/profile/15331394346374084727noreply@blogger.com3tag:blogger.com,1999:blog-4272166763501158655.post-59954665367880159672008-04-27T21:25:00.002-06:002008-04-27T21:32:38.241-06:00

Another article that I read about anti-inflammatories discussed the benefits of acupuncture on different inflammatory diseases. I really liked this article because it went into pretty good detail about the different inflammatory diseases as well as the effect the acupuncture had on them. Their results showed that acupuncture mainly benefitted patients with asthma. The acupuncture also seemed

JoAnnaD495http://www.blogger.com/profile/16995000415081003844noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-38090112723244412542008-04-27T21:01:00.002-06:002008-04-27T21:13:56.218-06:00

As i was looking for different alternative anti-inflammatories, I came across a few articles that suggested the use of stinging nettles, particularly to ease the pain caused by rheumatoid arthritis. The stinging nettle is a plant whose stinging hairs on are sharp, polished spines that contain histamine and formic acid. Normally these stinging hairs are painful to the touch but when they come

JoAnnaD495http://www.blogger.com/profile/16995000415081003844noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-57827851862583741132008-04-27T19:57:00.002-06:002008-04-27T20:20:03.526-06:00

This week, all of the lay articles seemed to have a common theme: Watch what you eat, and you will succeed in your endevor to become a healthy individual. This is a concept that is not particularly striking and an idea we have previously discussed in class. As a recap, roughly 60% of the American public is clinically over weight, and from articles we have previously read in this class,

SarahD495http://www.blogger.com/profile/09996651755315338786noreply@blogger.com2tag:blogger.com,1999:blog-4272166763501158655.post-73948763883286118152008-04-26T19:06:00.001-06:002008-04-26T19:31:28.074-06:00

The most recent group of papers sent to us included two seperate papers making reference to chocolate and its anti-inflammatory effects. The first was "Snacking in the Line of Duty." Here was a very quick reference to flavanols which "relax blood vessels, improve blood flow, decrease blood clotting and redue inflammation." The second article was "Chocolate 'has health benefits'". After

jeff rhttp://www.blogger.com/profile/17758102113757051453noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-22155461629077616702008-04-26T12:18:00.005-06:002008-04-26T12:42:54.608-06:00

Gastrointestinal toxicity of NSAIDS appears to be due to a “topical” effect and inhibiting of COX-1; where as, selective COX-2 inhibitors show great GI tolerability. The “topical” component in the pathogenic mechanism for damage is thought to involve the uncoupling of mitochondrial oxidative phosphorylation with increasing intestinal permeability. (The "topical" effect may be due to the

JackieE499http://www.blogger.com/profile/00569628992122703068noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-84140597142224870182008-04-24T10:53:00.003-06:002008-04-24T11:21:53.494-06:00

I thought it was very interesting that Kerry brought up the adverse effects of NSAIDs on asthmatic people, so I did some research to see if a mechanism had been found.I came across an article from the June 2007 edition of the journal Allergy (vol. 62). Wang, X.S. et al were able to culture mast cells (cells that are like basophil granulocytes and are involved in allergies) from peripheral blood

LaurenT495http://www.blogger.com/profile/11579353492843490313noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-39943427710204665812008-04-23T17:13:00.001-06:002008-04-23T17:16:18.428-06:00

Celecoxib, marketed as Celebrex, is an NSAID commonly used in the treatment of rheumatoid arthritis. Celebrex hit the market just under 10 years ago as an “alternative” NSAID with the same pain relief but fewer adverse gastrointestinal effects than “conventional” NSAIDS like ibuprophen and naproxen. As an “alternative” NSAID, Celebrex is a highly selective COX 2 inhibitor, whereas the “

AmyY495http://www.blogger.com/profile/07143709406839844436noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-4615274622098278252008-04-23T11:23:00.005-06:002008-04-23T12:11:12.981-06:00

Last week the benefits and subsequent risks associated with COX1 and COX2 selective inhibitors were discussed in terms of peripheral expression. This week the COX isoforms and inhibitors were reintroduced, although this time across the blood-brain barrier in global cerebral ischemia. Two COX inhibitors were used, the highly selective COX2 inhibitor Rofecoxib, and the COX1 inhibitor Valeryl

GabrielleB495http://www.blogger.com/profile/17477111273513712905noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-22835138369483166892008-04-22T23:59:00.002-06:002008-04-23T00:05:20.504-06:00

In this week’s reading, “Comparison of the Intestinal Toxicity of Celecoxib, a Selective COX-2 Inhibitor, and Indomethacin in the Experimental Rat,” it mentions that non-steroid anti-inflammatories or NSAIDs are implicated in gastrointestinal and small bowel side effects. To put this into context, I looked up what exactly these side effects include, and found that NSAIDs can cause ulcers,

KerryR495http://www.blogger.com/profile/15826036749157139087noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-5024898261643137082008-04-22T22:30:00.002-06:002008-04-22T23:04:01.799-06:00

There have been several factors that can lead to the damage of the gastrointestinal tract from NSAID's. There are two main mechanisms for the damage, one involves a the uncoupling of mitochondrial oxidative phosphorylation while the other is the inhibition of COX-1. For the peer review articles this week, it was suggested that the inhibition of COX-2 would suppress the prostaglandin synthesis at

AustinG495http://www.blogger.com/profile/05028873289448543813noreply@blogger.com2tag:blogger.com,1999:blog-4272166763501158655.post-23332877449112500412008-04-21T17:20:00.003-06:002008-04-21T17:39:50.407-06:00

After reading this lay article I found several points that left a bad taste in my mouth. One of the key problems I found was the author's lack of significant proof. When he finally mentioned some numbers to back up the suggestions they were scarce and prove nothing. Out of the original 76 rhesus monkeys only 50 are still alive. There is no mention here about how many were from the

jeff rhttp://www.blogger.com/profile/17758102113757051453noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-23236108354840756622008-04-20T17:29:00.002-06:002008-04-20T17:37:08.027-06:00

In class last week it was discussed about the safety of warfarin compared to heparin. I've recently looked up a article from the FDA stating that possible deaths related to heparin use could be higher than expected. I posted the link below and there is another link within the article that shows figures from Jan. '07 to March '08. My personal view of the article is probably the same as any other

AustinG495http://www.blogger.com/profile/05028873289448543813noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-16785474977626454582008-04-17T17:20:00.001-06:002008-04-17T17:22:34.068-06:00

Warfarin and Heparin are two common anticoagulants used to prevent thrombosis. They are both very effective at what they do, but come with some serious risks. Warfarin (market brand Coumadin) is a natural chemical found in plants that was originally marketed as a rat pesticide. Research uncovered Warfarin’s relatively safe and effective use as an anticoagulant not long after. If used at a

AmyY495http://www.blogger.com/profile/07143709406839844436noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-59281484142821730132008-04-16T13:41:00.002-06:002008-04-16T14:49:19.480-06:00

Acetaminophen and Ibuprofen, the active ingredients contained in Tylenol and Advil respectively, are two of the most common over the counter pain analgesics. As with any medication, the side effects are dose-dependent, and may be elevated in conjunction with alcohol consumption. In a society that demands a disclaimer on our fast food coffee, it seems appropriate that these drugs should carry a

GabrielleB495http://www.blogger.com/profile/17477111273513712905noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-91405056203422213792008-04-16T06:27:00.002-06:002008-04-16T06:32:15.274-06:00

The articles for this week deal with the positive and negative actions of NSAIDs. This particular article primarily addressed a popular news topic: the increase in risk for cardiovascular and cerebrovascular events due to selective COX-2 inhibitors. These drugs looked promising for pain relief without the unwanted side affect of GI bleeding that occurs with COX-1 inhibition. However, in September

LaurenT495http://www.blogger.com/profile/11579353492843490313noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-87321446005284704752008-04-15T21:07:00.000-06:002008-04-15T21:08:00.849-06:00

Warfarin or the generic form Coumadin is a commonly used prescription drug that is used to prevent stroke in patient suffering from chronic atrial fibrillation, a heart valve replacement, and/or a recent heart attack. Warfarin is usually referred to as a "blood thinner" or anticoagulant because it keeps blood flowing smoothly throughout the body by decreasing the amount of clotting proteins in

AustinG495http://www.blogger.com/profile/05028873289448543813noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-88151057298512468332008-04-11T22:47:00.003-06:002008-04-11T22:53:20.874-06:00

The Cyclooxygenase enzyme, also known as COX, is responsible for prostaglandin synthesis. There are two isoforms that were studied in this paper, COX-1 and COX-2. COX-1 is constitutively expressed; whereas, COX-2 is known as the inducible isoform. These enzymes serve a variety of functions in several vital regions of the body, but for time sake I will just discuss a few examples of their

JackieE499http://www.blogger.com/profile/00569628992122703068noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-74170548866782055802008-04-10T17:18:00.003-06:002008-04-10T17:38:15.447-06:00

Since we learned in PSIO 480 that caffeine may play a role in decreasing the incidence of Parkinson’s Disease (PD), I wondered if there was any more recent research on this. I found this study by Singh et al published this past February in the journal Brain Research.Although previous studies have shown neuroprotective effects of caffeine and nicotine against PD (see article’s references), no

LaurenT495http://www.blogger.com/profile/11579353492843490313noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-57426133243546387112008-04-09T20:03:00.002-06:002008-04-09T20:12:10.481-06:00

The articles we have read about Alzheimer's have focused on the amyloid-beta pathology. The other part of Alzheimer's disease is the formation of neurofibrillary tangles. Neurofibrillary tangles are composed of tau proteins that have abnormally formed because of overactive enzymes. Tau proteins are a microtubule associated protein. Tau proteins are important for assembling tubulin monomers into

lhtsosiehttp://www.blogger.com/profile/14584306614655142149noreply@blogger.com2tag:blogger.com,1999:blog-4272166763501158655.post-66054805354101104412008-04-09T14:52:00.004-06:002008-04-09T15:00:35.920-06:00

I found this article of a study done.  It says that eating aple related product could help with memory loss and alzheimer like symptoms.Here the link to itwww.brightsurf.com/news/headlines/22731/Age-related_memory_improvement_linked_with_consumption_of_apple_products.htmlFor other neurological degenerative news here's another linkwww.molecularneurodegeneration.com/news

dank495http://www.blogger.com/profile/17252486598014246996noreply@blogger.com4tag:blogger.com,1999:blog-4272166763501158655.post-34100645055223324682008-04-09T14:46:00.000-06:002008-04-09T14:47:01.434-06:00

I was really interested in the Bee sting therapy of Multiple sclerosis which is also known as apitherapy. According to A Randomized Crossover Study of bee sting therapy for Multiple sclerosis, apitherapy has no significant affect on M.S. patients. So I tried to see if there were any other studies out there that say otherwise. Most of what is out there is proposed studies; very little research has

Ashleym495http://www.blogger.com/profile/14392001097313294780noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-47538071205402876472008-04-07T16:53:00.004-06:002008-04-07T17:12:16.939-06:00

In Anura Rambukkana's study, published in Nature Medicine, showed that the leprosy bacteria, Mycobacterium leprae, attaches to myelinated Schwann cells and induces rapid demyelination. This demyelination can occur in the absence of immune cells, which is the cause of demyelination in neurodegenerative diseases, but the process is chronic and relatively slow despite high levels of the M.

AshleyF495http://www.blogger.com/profile/15331394346374084727noreply@blogger.com2tag:blogger.com,1999:blog-4272166763501158655.post-73889188054444514192008-04-06T19:41:00.002-06:002008-04-06T20:28:52.873-06:00

MS is a demyelinating disorder of the CNS (these axons unlike in the PNS cannot regenerate themselves) Treatment of MS does not invlove ridding the patient of the disease. Medical limitations allow only to alleviate the symptoms in hopes of the patient leading as normal a life as possible. Because of this, many people suffering with MS are open to trying alternative therapy, one includes bee

KimiH492http://www.blogger.com/profile/18216005063376928535noreply@blogger.com4tag:blogger.com,1999:blog-4272166763501158655.post-24295110425735881662008-04-06T18:50:00.002-06:002008-04-06T19:34:39.307-06:00

A characterisitc of Alzheimer's Disease in neurofibrillary tangles and amyloid plaques. It is these amyloid plaques that are beleived to be the reason for neurodegenitive degradation by acting either as a neurotoxin or an inflammatory response. Fibrinogen (a precursor to and the inactive form of Fibrin) is a stabilizing component of blood clots. Typically it is not seen in the central nervous

KimiH492http://www.blogger.com/profile/18216005063376928535noreply@blogger.com3tag:blogger.com,1999:blog-4272166763501158655.post-71067510657819639942008-04-05T22:18:00.001-06:002008-04-05T22:20:24.548-06:00

Parkinson’s Disease is a disease involving the degeneration of neurons in the substantia nigra. Many of these neurons contain the neurotransmitter dopamine. The degeneration of these neurons decreases the level of dopamine leading to an imbalance in the way muscles work and problems with movement.Cures for Parkinson’s are idiopathic, however, studies have found treatments to the disease. One such

BrookeJhttp://www.blogger.com/profile/00218243495690964892noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-47078680436551421142008-04-03T20:59:00.002-06:002008-04-03T21:07:52.889-06:00

In class the question was brought up about how depression affects memory loss. In the article "In Search of Lost Time," the author mentions how memory loss can be caused by depression, anxiety, and trouble sleeping. I looked back at the PSIO480 notes and found out how dopamine is involved in depression, anxiety, and trouble sleeping. The dopamine is a neurotransmitter and the pathway begins in

lhtsosiehttp://www.blogger.com/profile/14584306614655142149noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-2185477673674886042008-04-02T10:08:00.002-06:002008-04-02T10:33:01.801-06:00

In the "Inflammation in MS" review, the DR-17 haplotype was associated with autoimmune disorders such as diabetes, lupus, and thyroid disorders. In fact the more general Human Leukocyte Antigens (HLA) were found as the cell surface antigens mediating the rejection of tissue transplants in HLA mismatched donors. HLA-DR family is a major histocompatibility complex (MHC II) cell surface receptor and

AshleyF495http://www.blogger.com/profile/15331394346374084727noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-36343910052167131872008-04-01T23:21:00.001-06:002008-04-01T23:23:31.378-06:00

Alzheimer’s disease is a neurodegenerative disease that I took interest in because people spend their whole lives using cognitive function to create who they are. For some people the latter years of life are spent loosing all that function that was meticulously fostered to define them. Alzheimer’s is the most common cause for Dementia, its cause and progression are not clearly known and there are

Ashleym495http://www.blogger.com/profile/14392001097313294780noreply@blogger.com2tag:blogger.com,1999:blog-4272166763501158655.post-78692036719737620942008-04-01T22:16:00.002-06:002008-04-01T22:18:16.333-06:00

I was researching cures/relief mechanisms for arthritis and something really caught my eye. Sea bathing. I really don’t know if it’s fact or fiction. I’ve searched high and low and all I’ve gotten are mixed theories and beliefs. Many articles state that sea bathing is a beneficial treatment for arthritis. The main constituent in the sea water valuable for pain relief of arthritis is iodine.

BrookeJhttp://www.blogger.com/profile/00218243495690964892noreply@blogger.com3tag:blogger.com,1999:blog-4272166763501158655.post-34460076458750521192008-04-01T22:07:00.004-06:002008-04-01T22:40:00.830-06:00

Calorie restriction seems it may have a neuroprotective effect in ageing or age-related diseases, though the mechanism is not quite clear. In a study from the National Institute on Ageing found that adult mice showed an increase in neuron generation in the hippocampus, than mice on a normal diet. The dietary restriction boosts factors such as brain-derived neurotrophic factor (BDNF), which

AshleyF495http://www.blogger.com/profile/15331394346374084727noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-57176855618696163062008-04-01T14:40:00.009-06:002008-04-02T14:59:27.334-06:00

A synovial joint consists of articulating bone surfaces that are covered with hyaline cartilage (aka articular cartilage) separated with a fluid filled space surrounded by a joint capsule. The lining of the joint space is covered with a synovial membrane. Synovial membranes are composed of cuboidal collagenous cells called synoviocytes, they function to secrete synovial fluid that aid

AmyS595http://www.blogger.com/profile/15379299685840148870noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-69567161699825160132008-03-31T21:37:00.002-06:002008-03-31T21:40:44.398-06:00

Inflammatory processes in the brain (and systemically) have been linked to neuron loss in CNS disease and injury, including Alzheimer’s Disease, Parkinson’s Disease, MS, stroke, etc. Inflammation in the brain can lead to increased expression of inflammatory mediators, cytokines being a primary one in the inflammatory response. The cytokine IL-1 has been shown to contribute to neuronal loss and

JackieE499http://www.blogger.com/profile/00569628992122703068noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-66842651813054758662008-03-31T17:40:00.003-06:002008-03-31T19:21:53.002-06:00

Dr. David Pisetsky, chief of the division of rheumatology and immunology at Duke University Medical Center have recently found the curative property of gold salts for rheumatoid arthritis and other inflammatory diseases. Dr. Pisetsky, working with other scientists at Karolinska Institute in Sweden and the University of Pittsburg, have been studying the functional properties of HMGB1 molecules,

arlenej495http://www.blogger.com/profile/16614963142751531502noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-11058375714346411162008-03-29T14:28:00.003-06:002008-03-29T14:49:47.221-06:00

Matrix Metalloproteinases (MMPs) are enzymes considered to be responsible for cartilage bone damage. There are over 20 zinc-containing endopeptidases that include collagenases, gelatinases, stromelysins. MMPs are released as inactive but become active only when the propeptide is cleaved. MMPs have a key role in normal connective tissue remodeling and their activation, release, and inhibition (by

MariaO495noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-24128028536693943882008-03-29T12:16:00.002-06:002008-03-29T12:28:39.160-06:00

After class I was interested in what drugs were currently being used for the treatment of RA and how they worked. I work in a pharmacy and spoke with one of my pharmacists. He said that usually corticoids are usually used first, primarily because they are less expensive. Next in line are DMARDS, disease-modifying antirheumatic drugs. Common ones are methotrexate, hydrochloroquine, among

ChristinaS495http://www.blogger.com/profile/02690755343984973920noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-73918362968962961642008-03-26T15:49:00.000-06:002008-03-26T15:50:41.543-06:00

The paper “Enhanced and Coordinated in Vivo Expression of Inflammatory Cytokines and Nitric Oxide Synthase by Chondrocytes from Patients with Osteoarthritis” was quite interesting because it compared the inflammatory activity at arthritic joints from two sources—the synovial membrane and the cartilage within the joint. The paper divides the four test arthritises, rheumatic, psoriatic,

AMSTitanicnoreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-68494884179175081042008-03-24T13:19:00.002-06:002008-03-24T15:07:02.785-06:00

Researchers from the University of California, San Diego are experimenting with targeting the central nervous system in an attempt to control immune and inflammation response in RA and OA. Using a rat model with RA, they found the could successfully decrease inflamation and destruction of joint tissue by injecting substances into the spinal cord thereby inhibiting the signal from the brain that

KimiH492http://www.blogger.com/profile/18216005063376928535noreply@blogger.com2tag:blogger.com,1999:blog-4272166763501158655.post-81022669401916865312008-03-13T15:33:00.002-06:002008-03-13T16:17:20.029-06:00

This articles expressed the significance of SOD in neutralizing the superoxide anion from ROS that plays a vital role in inflammation, especially in inflammatory joint diseases. Proinflammatory factors (cytokines, prostaglandins) are released at sites of inflammation with ROS and NO. These are associated with decreased SOD concentrations in joint fluid, which are important in the protection

JackieE499http://www.blogger.com/profile/00569628992122703068noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-11355910109374996842008-03-12T15:05:00.002-06:002008-03-12T15:08:36.732-06:00

In the review article “Molecular Aspects of Pathogenesis in Osteoarthritis: The Role of Inflammation” I found several tidbits interesting. In osteoarthritis , the inflammation factor is actually very low compared to other forms of arthritis however IL-1 and TNF-α have been found in the synovial fluid of osteoarthritis (OA) patients. While the cause of OA is unknown, one idea is that the loss (

AMSTitanicnoreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-89818385637130482702008-03-12T14:13:00.002-06:002008-03-12T15:05:33.971-06:00

In the article "Can Diet or Supplements Relieve Your Arthritis Aches and Inflammation?" The phrase phytonutrients like flavonoids caught my attention as I’d never heard of flavonoids before. Phytonutrients are simply components thought to promote human health that are derived from plants. Some commonly known phytonutrients are carotenoids such as alpha and beta carotene. Flavonoids are compounds

AMSTitanicnoreply@blogger.com2tag:blogger.com,1999:blog-4272166763501158655.post-15907072620954295332008-03-11T21:49:00.002-06:002008-03-11T22:29:23.410-06:00

The article "Can Diet or Supplements Relieve Your Arthritis Aches and Inflammation" in Environmental Nutrition addressed the issue of the increased use of dietary supplements among suffers of arthritis. While many companies advertise the benefits of their product, there are many doubts as to their effectiveness within the scientific community. While some products may offer some relief from

AmyS595http://www.blogger.com/profile/15379299685840148870noreply@blogger.com2tag:blogger.com,1999:blog-4272166763501158655.post-68984869883236475132008-03-11T21:07:00.008-06:002008-03-11T22:21:25.539-06:00

I was just reading the article "Can Diet or Supplements relieve your Arthritis aches and Inflammation" assigned for this week. It talks about the various dietary supplements that Arthritis patients take in order to ease some of the symptoms of Arthritis: pain, aches, stiffness and swelling around the joints. Arthritis patients have an overactive immune system which leads to the breakdown of the

arlenej495http://www.blogger.com/profile/16614963142751531502noreply@blogger.com3tag:blogger.com,1999:blog-4272166763501158655.post-62337341931804876712008-03-11T14:10:00.002-06:002008-03-11T14:47:52.591-06:00

Hello everyone, I was reading the articles this week and there was one I found particularly interesting. I liked the article CNS Can Control Arthritic Joint Inflammation and Destruction. Researchers at the University of California, San Diego tried a new approach to treating arthritic joint inflammation and destruction. The researchers believed the CNS is a controlling influence for the body

ChristinaS495http://www.blogger.com/profile/02690755343984973920noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-32391189292696841662008-03-10T12:06:00.003-06:002008-03-10T14:10:23.800-06:00

I came across this very interesting case study and wanted to share it with all. Parenteral nutrition (intravenous feeding) and enteral nutrition (tube feeding) with an elemental diet have been proven to control CD activity. This treatment is not widely used because it is expensive and has side effects. However, in this particular case study total disease remission was induced with non-elemental

MariaO495noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-81619291940880925722008-03-07T01:02:00.002-07:002008-03-07T01:03:46.428-07:00

I too, was unable to access the article Zoe recommended us read regarding worms as treatment for IBD. However, I did find another article on WebMDHealth pertaining to the same information. This article plainly states that “Parasitic Worms Ease IBD.” It briefly explains the wormy treatments and research for IBD conducted under gastroenterologist Robert W. Summers, MD, of the University of Iowa,

BrookeJhttp://www.blogger.com/profile/00218243495690964892noreply@blogger.com2tag:blogger.com,1999:blog-4272166763501158655.post-90808931678896775442008-03-06T02:41:00.003-07:002008-03-06T02:45:04.662-07:00

We all understand that a stroke occurs when a blood vessel in the brain becomes blocked by a clot or bursts, eventually leading to decreased O2 and glucose supply to that particular brain tissue. As a result, this tissue will either become damaged or die. However, according to Lauralee Sherwood, there is a lot more to the causes of brain damage than what’s been told. She calls it “A Deadly

BrookeJhttp://www.blogger.com/profile/00218243495690964892noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-81614891427184159052008-03-05T18:18:00.004-07:002008-03-05T18:52:08.865-07:00

Hi Everybody. I was intrigued and a little disturbed by this article, which talked about the association between sugar consumption, smoking and Crohn's Disease. They used added sugar as an estimate because it is highly correlated with overall refined sugar intake, typically making up about half of it. Furthermore, smokers take in about one-third more sugar than non-smokers. Both smoking and sugar

JackieE499http://www.blogger.com/profile/00569628992122703068noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-15672471751220543082008-03-05T12:01:00.002-07:002008-03-05T12:20:19.638-07:00

Hi Class,I found some interesting information on the relationship between Crohns and TNF alpha. As we all know, TNF alpha plays a role in chemotaxis of white blood cells to fight infection or pathogens. A somewhat new drug, Infliximab, is FDA approved and is used to very selectively target and antagonize TNF alpha . Antagonizing TNF alpha would disable the release of cytokines such as

brandonc495http://www.blogger.com/profile/09767352613492023568noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-27509298644943945742008-03-04T19:35:00.002-07:002008-03-04T19:57:01.844-07:00

Hey everyone-I found an article about an unusual treatment for IBD. Apparently, cannabis can alleviate symptoms of IBD. A group did some research on why, and they had some interesting findings. They looked at two specific receptors in the gut, CB1 and CB2, which are activated by cannabis. CB1 is present in healthy individuals, but CB2 is more prevalent in people that suffer from IBD. CB2 levels

TomF495http://www.blogger.com/profile/09589441211155362407noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-65825995998137331362008-03-03T19:19:00.002-07:002008-03-03T20:26:07.677-07:00

Hi everyone:DA couple of things from this article caught my attention. Prior to reading this (and a few other papers) I had heard of Crohn's disease, UC, and IBD but I didn't have very much knowledge about them. So I found it interesting that in IBD basically the immune system kicks into high gear because it recognizes its own intestinal flora as a pathogen. This elicits an immune response

KimiH492http://www.blogger.com/profile/18216005063376928535noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-87819761391562526272008-03-02T18:06:00.006-07:002008-03-03T10:32:15.661-07:00

Hey Class! I wanted to share this article I found because I think it puts the disease in perspective of how pervasive it can be and its application to children. Crohn's Disease is not usually diagnosed at young ages but rates are continually increasing. This paper describes three cases individually who were medically therapy - resistant and had extremely poor qualities of life. I did not

LianH495http://www.blogger.com/profile/05916419830794686951noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-1677623750876578912008-02-29T18:35:00.002-07:002008-02-29T18:38:29.927-07:00

I tried to access the parasitic worm article that Dr. Cohen posted but couldn’t without subscribing so I did a little snooping around to see what I could find out about the Helminthic Therapy. As discussed in class, this is the method of trying to treat IBD by ingesting thousands of these parasitic worms. Apparently, researchers decided to try this out after seeing the positive correlation

huyn495http://www.blogger.com/profile/08046954788422446514noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-507374904658117172008-02-27T19:35:00.002-07:002008-02-27T20:29:57.429-07:00

A large part of this article talked about several primary events seen in patients with inflammatory bowel disease. First, people with IBS tend to have leaky epithelial barriers(increased permeability) preceding the onset of disease. Furthermore, healthy individuals that are first-degree relatives of patients with IBD also show permeability defects. I am curious as to why this does not lead to the

JackieE499http://www.blogger.com/profile/00569628992122703068noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-8010520403705985652008-02-27T14:45:00.001-07:002008-02-27T14:47:08.616-07:00

While reading the articles, I realized that I wasn't really aware of what the symptoms for Crohn's disease were, so I'm posting this link to the mayo clinic website that describes them briefly in case anyone else was unsure.http://www.mayoclinic.com/health/crohns-disease/DS00104

SarahD495http://www.blogger.com/profile/09996651755315338786noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-9767279229259987682008-02-27T12:33:00.002-07:002008-02-27T12:37:22.938-07:00

Here's an interesting paper related to a novel treatment of IBD."In a stunt reminiscent of the TV reality show Fear Factor, dozens of unpaid volunteers have recently been gulping Gatorade laced with 2500 live eggs from parasitic worms"http://www.sciencemag.org/cgi/reprint/305/5681/170?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext=worms+immune&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT.pdf

ZoeC495http://www.blogger.com/profile/02159968024013028357noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-11350272021251882682008-02-27T10:43:00.004-07:002008-02-27T11:17:04.251-07:00

After reading "Translational Research in Inflammatory Bowel Disease" the role of dendritic cells in pathogenesis of IBD interested me. A little info : All dendritic cells are derived from bone marrow progenitor cells and once differentiated, are termed "immature" dentritic cells. These immature cells constantly "sample" their environement for viruses, bacteria, and other pathogens via high

brandonc495http://www.blogger.com/profile/09767352613492023568noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-87155086160598761652008-02-26T20:11:00.003-07:002008-02-26T20:38:29.311-07:00

The article entitled "Translational Research in IBD" mentions antagonizing Th1 cytokines without really explaining why this is an effective treatment option for IBD...so I looked into it. First, upon seeing an antigen piece presented to it, helper T cells will differentiate into either Th1 or Th2 cells (just type 1 or type 2 helper T cells). Both these T cells will then produce cytokines and

TomF495http://www.blogger.com/profile/09589441211155362407noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-64870711481150412492008-02-26T20:05:00.002-07:002008-02-26T20:13:48.456-07:00

The Newsweek article posted talks about all of the wonders and benefits of probiotics and reminded me of a news story I had heard. I guess Dannon (yogurt company) is one of those companies that has been using probiotics and marketing the effects of them, especially in digestion. Anyways, there's been a recent lawsuit placed against them, claiming that Dannon has mislead consumers and claiming

huyn495http://www.blogger.com/profile/08046954788422446514noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-73873495420331398812008-02-26T19:59:00.002-07:002008-02-26T20:04:46.758-07:00

As mentioned by Lian, Inflammatory Bowel Disease (IBD) is an overactive and uncontrolled immune response in the digestive tract. The article assigned this week, “Translational Research in Inflammatory Bowel Disease” (Abreu et. al) contains a good amount of information regarding the disease. The researchers identify that IBD is caused by a dysregulated mucosal immune response to a luminal antigen

huyn495http://www.blogger.com/profile/08046954788422446514noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-77236141829928742312008-02-23T15:50:00.003-07:002008-02-23T16:17:06.980-07:00

One of the leading causes of stroke is atrial fibrillation, a condition which causes the upper two chambers of the heart to beat irregularly. In atrial fibrillation, the electrical impulses that are normally generated by the sinoatrial node are replaced by disorganized activity in the atria, leading to irregular conduction of impulses to the ventricles that generate the heartbeat. The result is

JoAnnaD495http://www.blogger.com/profile/16995000415081003844noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-78436893302521422002008-02-23T14:23:00.011-07:002008-02-23T15:43:18.565-07:00

Inflammatory Bowel Disease is a general categorization for multiple diseases that are distinguished by an abnormal immune response found in the digestive tract. Often healthy microbes such as certain types of bacteria are mis recognized, and the immune system responds by sending white blood cells to the intestinal lining. This immune response unfortunately results in chronic inflammation

LianH495http://www.blogger.com/profile/05916419830794686951noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-11197612565749751722008-02-21T23:53:00.004-07:002008-02-22T03:15:51.093-07:00

As we read in this weeks articles, interleukin 10 (IL10) is an anti-inflammatory cytokine that helps reduce the damage caused by inflammation after a stroke. I did more research on this cytokine and found in the paper, Interleukin-10 Modulates Neuronal Threshold of Vulnerability to Ischaemic Damage, that the source of IL-10 in the brain is activated microglia. This superised me, because

KerryR495http://www.blogger.com/profile/15826036749157139087noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-46750378061785343092008-02-21T14:48:00.001-07:002008-02-21T14:51:14.234-07:00

I am also very interested in why Mexican Americans are more suseptible to stroke. I looked up a bunch of articles and found one study that showed a much lower average age of Mexican American stroke sufferers to that of non-hispanic whites. They also found a that Mexican Americans were less likely to have graduated high school and more likely to make less than 20K per year, which could have been

JackieE499http://www.blogger.com/profile/00569628992122703068noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-88911804124281374312008-02-20T14:44:00.001-07:002008-02-20T14:49:06.214-07:00

The basic science paper assigned this week (“Levels of Anti-Inflammatory Cytokines and Neurological Worsening in Acute Ischemic Stroke” by Nicolas Vila et. al.) Another element that plays a role in reducing the damaging effects of ischemic stroke was introduced: Interleukin-10 (IL-10). IL-10 is a cytokine which acts as an anti-inflammatory agent, by inhibiting the production of some

JamesH495http://www.blogger.com/profile/15248846001031459547noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-13475938666179369572008-02-20T13:27:00.006-07:002008-02-20T14:21:56.763-07:00

I noticed in two of the four readings that there was the mention of using fucoidin.  So I thought I would look up to see what fucoidin is and where it comes from.  Fucoidin is a sulfated polysaccaride found in types brown seaweed and also within animals such as the sea cucumber.  There are two types of fucoidin (also spelled fucoidan and fucidin) F-fucoidin which is composed of greater then 95%

dank495http://www.blogger.com/profile/17252486598014246996noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-56127317729749009422008-02-19T20:30:00.002-07:002008-02-19T20:35:31.654-07:00

So this article basically tells the dangers that mexican-americans deal with as a risk for stroke. However, the article describes other risk factors for stroke; poor diet, physical inactivity, smoking, not going to the doctor proceeding a stroke, high blood pressure and cholesterol, diabetes, etc. Why do you think this would target mexican-americans over any other race. Americans pretty much

KimiH492http://www.blogger.com/profile/18216005063376928535noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-77494895491899182652008-02-19T17:47:00.003-07:002008-02-19T17:48:48.670-07:00

Does anyone know why birth control pills can increase your risk of stroke?

MargaretO495http://www.blogger.com/profile/09079283530627304529noreply@blogger.com5tag:blogger.com,1999:blog-4272166763501158655.post-10382996306815364922008-02-19T12:54:00.002-07:002008-02-19T13:13:42.590-07:00

The previous articles focus on inflammation and disease. In lecture I had remembered Zoe discussing about the Guillain-Barre syndrome (GBS) which is somewhat relevant to the articles. So now I am passing on the notes. GBS is an acute inflammatory demyelinating polyneuropathy. It is normally triggered by an acute infectious process and affects the peripheral nervous system. The notes in

BrookeJhttp://www.blogger.com/profile/00218243495690964892noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-19532152131460933342008-02-18T22:22:00.004-07:002008-02-18T23:12:55.235-07:00

Towards the end of our last discussion the question came up about neuron regeneration. There are actually two two different types of neurons that are able to regenerate. We have been taught and had the understanding for the longest time that neurons do not regenerate...thus don't go running around and getting too many concussions. However there has been research completed that says otherwise:

LianH495http://www.blogger.com/profile/05916419830794686951noreply@blogger.com2tag:blogger.com,1999:blog-4272166763501158655.post-53464160915854076102008-02-13T20:09:00.003-07:002008-02-13T20:34:38.981-07:00

I am providing you with ample justification of the health benefits of alcohol consumption. The link provided is a study that investigated the effects of wine on inflammation. The blood concentration of inflammation markers C-reactive protein and fibrinogen were measured, however only fibrinogen levels decreased (...slightly) upon moderate wine consumption. The name 'C-reactive protein' sounds

GabrielleB495http://www.blogger.com/profile/17477111273513712905noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-52059338216537794892008-02-13T14:39:00.002-07:002008-02-13T14:42:54.111-07:00

Hi class. I was just wondering how ischemia causes damage to the blood brain barrier, which in turn allows leukocytes and neutrophils access to the infarction site. I understand how the microglia change metabolically and chemically to become phagocytic during ischemia; does this possible have something to do with the breakdown of the B.B.B. at the site?

brandonc495http://www.blogger.com/profile/09767352613492023568noreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-21414792696768817212008-02-13T10:12:00.001-07:002008-02-13T10:59:10.111-07:00

In the article, Nitric Oxide, ischaemia and brain inflammation, nitric oxide and nitric oxide synthase (NOS) isoforms are shown to be implicated in stroke pathophysiology. In a cell, nitric oxide can mutate DNA, inhibit the electron transport chain, and either promote or protect the cell from apoptosis. There are three isoforms of NOS: neuronal NOS-1, inducible NOS-2, and endothelial NOS-3.

KerryR495http://www.blogger.com/profile/15826036749157139087noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-38896394468043705272008-02-13T04:57:00.002-07:002008-02-13T05:07:56.806-07:00

As mentioned in our readings, stroke is one of the more common causes of death or disability. It is characterized as damage to the brain due to loss of blood flow by way of one of the two causes mentioned in the previous post. Either a blockage develops in the arteries of the brain (ischemia), or a rupture occurs, leading to a hemorrhage. Several elements related to inflammation are involved

JamesH495http://www.blogger.com/profile/15248846001031459547noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-132546826126152382008-02-12T21:01:00.002-07:002008-02-12T23:00:00.296-07:00

 Hello class, to give everyone a little background strokes are categorized into two different types: ischemic and hemorrhage.  Ischemic strokes are caused by either a thrombosis or an embolism.  Hemorrhage strokes are either intracranial or intracerebral.  And if you are wondering what kind of stroke you can look forward to dying from and at what percent, then I am glad to inform you that you are

dank495http://www.blogger.com/profile/17252486598014246996noreply@blogger.com0tag:blogger.com,1999:blog-4272166763501158655.post-63429977233247920282008-02-10T15:17:00.000-07:002008-02-10T15:54:21.877-07:00

Here is the passage i read at the end of our last discussion..."Interleukin-6 (IL-6) could mediate some of the health beneficial effects of exercise. In resting muscle, the IL-6 gene is silent, but it is rapidly activated by contractions. The transcription rate is very fast and the fold changes of IL-6 mRNA is marked. IL-6 is released from working muscles into the circulation in high amounts. The

BobbyD495http://www.blogger.com/profile/01471059034086722962noreply@blogger.com3tag:blogger.com,1999:blog-4272166763501158655.post-67534677165338902782008-02-06T14:32:00.000-07:002008-02-06T14:39:33.573-07:00

So this is just a question I wanted to throw out there for anyone to answer. While I was reading the article that discussed the relationship of body fat mass and distribution to markers of chronic inflammation, it was stated that IL-6 has been shown to predict cardiovascular disease. I've heard this before, but I was wondering if anyone knew how this correlation was found and how this prediction

SarahD495http://www.blogger.com/profile/09996651755315338786noreply@blogger.com2tag:blogger.com,1999:blog-4272166763501158655.post-36038259407677734282008-02-04T14:20:00.000-07:002008-02-04T14:22:39.579-07:00

Last week we talked about how the human brain doesn't have an immune response and white cells can recognize the brain as "foreign" so just came across this article and thought it was interesting...http://www.nytimes.com/2008/02/05/health/05pork.html?pagewanted=1&_r=1&hp

AMSTitanicnoreply@blogger.com1tag:blogger.com,1999:blog-4272166763501158655.post-37368665501939918162008-02-01T17:34:00.000-07:002008-02-01T19:05:05.949-07:00

The markers of chronic inflammation and obesity have a "tag you're it" kind of effect. The first marker to be "it" is TNF-a which in turn tags IL-6. IL-6 then induces CRP synthesis. Elevated blood concentrations of TNF-a, IL-6 and CRP indicate that there is an inflammatory condition occuring in your body which also stimulates obesity. The theory though, is that exercise and diet will reduce

BrookeJhttp://www.blogger.com/profile/00218243495690964892noreply@blogger.com1